30 In Focus: Nir Eyal on (the deontology of) “Challenge Testing” a Covid Vaccine

On April 27, David D. Kirkpatrick reported in the N. Y. Times that Oxford’s Jenner Center is close to starting human trials on a potential Covid-19 vaccine. According to Kirkpatrick, “ethics rules, as a general principle, forbid seeking to infect human test participants with a serious disease. That means the only way to prove that a vaccine works is to inoculate people in a place where the virus spreading naturally around them.”

It ain’t necessarily so, says Nir Eyal, Henry Rutgers Professor of Ethics and Director of  Center for Population-Level Bioethics, Rutgers University.

Eyal is lead author (along with Harvard’s Marc Lipsitch and Peter Smith) of a striking March article in the Journal of Infectious Diseases, “Human Challenge Studies to Accelerate Coronavirus Vaccine Licensure.” A recent interview with Nir in Nature has a more revealing title: “Should scientists infect healthy people with the coronavirus to test vaccines?”

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