On April 27, David D. Kirkpatrick reported in the N. Y. Times that Oxford’s Jenner Center is close to starting human trials on a potential Covid-19 vaccine. According to Kirkpatrick, “ethics rules, as a general principle, forbid seeking to infect human test participants with a serious disease. That means the only way to prove that a vaccine works is to inoculate people in a place where the virus spreading naturally around them.”
It ain’t necessarily so, says Nir Eyal, Henry Rutgers Professor of Ethics and Director of Center for Population-Level Bioethics, Rutgers University.
So, John sat down with Nir to discuss the idea of deliberately exposing healthy young volunteers to corona virus in order to accelerate the efficacy phase of vaccine testing. Prior to this pandemic, many felt challenge testing with a deadly disease was beyond the ethical pale. Eyal et. al propose that despite its checkered history (think coerced deadly medical procedures), there is an interesting philosophical case to be made in its favor.
Want to read more coverage of challenge testing? Start with this Washington Post article, or this one.
Upcoming Episodes: Books in Dark Times returns next week with Australian scholar Vanessa Smith singing the praises of the uncategorizable Marion Milner–as well as one of John’s favorite novelists from Down Under. The following week, Modernist Paul Saint-Amour wins John’s heart by unpacking the metaphysics of time travel in such SF born-classics as Arrival, perhaps the most octopus/Heptapod-loving film of recent years.
The British filmmaker Mike Leigh puts the move into movies: he never stops changing, never stops inventing. In nearly 50 years of filmmaking, he has ranged from comic portrayals of ordinary life amid the social breakdowns of Thatcher’s Britain (Life is Sweet, High Hopes) to gritty renditions of working-class constraint and bourgeois hypocrisy (Meantime, Abigail’s Party, Hard Labour) to period films that reveal the “profoundly trivial” elements of artistic life even two centuries in the past (Topsy-Turvy, Mr. Turner).
Leigh (did you guess he was our Mystery Guest from the grainy photo we posted last week?) contains multitudes. What Roland Barthes says about the novels of Marcel Proust is true of Mike Leigh films as well: you notice different things every time you return to them.
When he sat down with John in Columbus, Ohio (at a Victorianist convention, no less!) they were united by love for a hometown boy made good: James Thurber. The conversation ranged from recording working-class voices in the 19th century to Method acting to the pointlessness of fetishizing closeups to the movies John had never seen and should have–and that’s only the first twenty minutes. It cries out for footnotes, but maybe the best result of all this talk would be simply your decision to go off and see a couple of (or four, or five, or like John seven) Mike Leigh films you’d never seen before. You won’t be sorry.
In this episode, John interviews the celebrated British writer Zadie Smith. Zadie’s horror at the idea of rereading her own novels opens the show; she can more easily imagine rewriting one (as John’s beloved Willa Cather once did) than having to go through them all again. From there the conversation quickly moves through Brexit (oh, the inhumanity!) and what it means to be a London–no, a Northwest London–writer before arriving at her case against identity politics. That case is bolstered by a discussion of Hannah Arendt on the difference between who and what a person is. As Zadie puts it, “When you say my people, you can[‘t] know for certain who those people are by looking at them and by hearing what they have to say. I think what fiction as a kind of philosophy always assumed is that what people make manifest is not all that people are. There’s a great part of human selves which are hidden, unknown to the self, obscure, and that’s the part that fiction is interested in.”
On this episode of Recall This Book, John talks to Stephen McCauley, a novelist and Professor of the Practice of English and Co-director of Creative Writing at Brandeis. Nobody knows more about the comic novel than Steve, and there is no comic novelist he loves better than Barbara Pym, a mid-century British comic genius who found herself forgotten and unpublishable in middle age, only to roar back into print in her sixties. Steve and John’s friendship over the years has been sealed by the favorite Pym lines they text back and forth to one another, so they are particularly keen to investigate why her career went in this way. Continue reading “Episode 5: The Comic Novel with Stephen McCauley”